Thursday, 10 May 2018

The incredibly frustrating reason there’s no Lyme disease vaccine

quote [ LYMErix had the misfortune of being approved the same year some people were becoming suspicious of vaccines in the United States. In 1998, the journal Lancet published a now-retracted study that (falsely) claimed the measles, mumps, and rubella vaccine (MMR) was linked to autism, and the modern anti-vax movement was born.

At the same time, a few members of the FDA panel that approved LYMErix had voiced a theoretical concern that the drug could cause an autoimmune reaction leading to arthritis. The idea was that as the immune system learned to attack the protein that covered the Lyme bacteria, it could overreact and start to attack healthy tissue in the body. This side effect didn’t occur in the clinical trial. It was just a hypothetical possibility. ]

Interesting read /25 chars
[SFW] [health] [+3 Interesting]
[by knumbknutz@9:52pmGMT]

Comments

zenviper said @ 12:56am GMT on 11th May [Score:2]
Funny you should post this as I was researching the topic myself this morning as well.

Two interesting take-away's I found:

1. There is a new vaccine in development that was approved for fast-track trials:
https://globenewswire.com/news-release/2017/07/24/1055914/0/en/VALNEVA-Receives-FDA-Fast-Track-Designation-for-its-Lyme-Disease-Vaccine-Candidate-VLA15.html

2. CDC funding for Lyme's is stupidly low relative to other diseases when you consider the number of incidents.
329,000 annual cases of Lyme Annually vs. 500-5,000 zika depending on how you count
$24 Million funding for Lyme vs. 1.9 Billion for Zika - nearly 80x more for Zika.

I had Lymes two years ago, and it was the sickest I have ever been in my life. I am a fit/healthy and relatively young person. The pain was immense, I was soaked in sweat with a fever and unable to leave bed for a little over a week. I was fortunate that my wife's family is from New England and was familiar with the illness and knew to get me on a course of treatment early - shortly before I ended up bedridden.

I am 100% better now, but for those that don't catch the disease early enough, it can persist for years, or life; known as chronic lyme, or persistent lyme.

Despite how widespread (and increasingly so) this disease is in the US, it is not well researched or well understood by the average doctor. Many doctors are dismissive and people don't get the treatment they need.

I don't often rant about issues on here, but having experienced this first-hand and not wanting anyone else to have to go through that type of suffering I hope that more people become aware of the issue and push for change.
HoZay said @ 1:31am GMT on 11th May
Push for change = vote for change. The outfit in charge now seems actively opposed to your good health
zenviper said @ 1:32am GMT on 11th May
Agreed - it is one avenue.
perezoso said[1] @ 12:40am GMT on 11th May [Score:1 Insightful]
But the real solution for a lot of vaccines is for the government to contract production and distribute them via our (increasingly endangered) public health system. The fundamental discoveries that enable pantloads of them were paid for by you and me - i.e. publicly-funded research - and the government has quite a bit of ability to shape how they are produced and sold. But the dotards of HHS, perhaps because of things like stock options and fat consulting fees, stubbornly refuse to assert those public interests. I don't know this vaccine in particular, but it's probably not expensive to produce, and it's apparently off-patent ... fucking greed for higher-than-generic profit margins and fear of liability stand in the way of the private sector.... so let the government do it. Even the good ole US Army has wanted a "GOCO" vaccine facility for years because they too have need for weird, commercially unviable jabs from time to time.

Or, to put it more simply, the frustration should be vented on the pharma pigs and not so much the misguided but genuine anti-vaxxers.
1111 said @ 1:05pm GMT on 11th May [Score:-2 Boring]
filtered comment under your threshold
rylex said @ 4:34pm GMT on 11th May [Score:-2]
filtered comment under your threshold

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